What tests should you consider for a patient heading to surgery?
ACC on preop EKG:
-
reasonable for patients with known coronary heart disease, significant
arrhythmias, peripheral artery disease, cerebrovascular disease, or
other significant structural heart disease, except for those having
low-risk surgery (IIa, B)
- may be
considered for asymptomatic patients without known coronary heart
disease, except for those undergoing low-risk surgery (IIb, B)
- not useful for asymptomatic patients undergoing low risk surgical procedures (III:NB, B)
-
timing: ACC notes general consensus that when EKG is warranted, an
obtained EKG 1-3 months prior to surgery is adequate for stable
patients. This is more an observation in the guideline rather than a
recommendation.
ICSI on preop EKG:
- agrees with ACC-AHA 2014 recommendations
ACC on preop eval of LV function:
– reasonable for patients with dyspnea of unknown origin (IIa, C)
– reasonable for patients with HF with worsening dyspnea or other change in clinical status (IIa, C)
–
reassessment may be considered in clinically stable patients with
previously documented LV dysfunction if there has been no assessment
within a year (IIb, C)
– routine preop eval of LV function is not recommended (III:NB, B)
ACC on preop eval of valve dz:
–
recommended for patients with clinically suspected moderate or greater
degrees of valvular stenosis or regurgitation if there has been either
(1) no prior echo within 1 year, or (2) a significant change in clinical
status or physical exam since last eval (I, C)
These
recommendations endorse a limited role for preop echocardiography. They
apply mostly to those with symptoms, severe disease, or both. They
are mostly permissive, lukewarm recommendations. The recommendation
against routine echo continues. And the evidence does not support clear
benefit. The retrospective cohort study (Wijeysundera BMJ 2011, see ref)
of 9 years of patients undergoing intermediate to high risk surgery in
Ontario hospitals compared 40,000 patients with preop echo to 70,000
propensity-score matched controls (always a tricky study design) without
echo. Preop echo was not associated with improved survival or hospital
stay
ICSI says consider checking K+ if:
- Patient takes Digoxin, diuretics, ACE inhibitor, or ARB
- check electrolytes for those on lithium
ASA's
2012 guideline mentions testing directed by clinical characteristics
including likely perioperative therapies, endocrine disorders, risk of
renal and liver dysfunction, and use of certain medications or
alternative therapies. ASA's Choosing Wisely document recommends no
preop CBC, BMP or CMP, or coags in patients without significant systemic
disease (ASA class I or II) undergoing low-risk surgery when blood loss
(or fluid shifts) is/are expected to be minimal.
Do not perform routine preop CXR.
Consider preop CXR if patient has signs or symptoms suggesting new or unstable cardiopulmonary disease.
Not
only does the ESA (gr B) guideline review the evidence of no benefit,
but 4 different organizations have identified preop CXR as a practice to
be discontinued in the Choosing Wisely campaign, namely the American
College of Physicians, the American College of Radiology, the American
College of Surgeons, and the Society of General Internal Medicine, each
offering their own review of the evidence.
ASA states that
extremes of age, smoking, stable COPD, stable cardiac disease, or
resolved recent upper respiratory infection should not be considered
unequivocal indications for chest radiography.
ICSI
says routine Hbg/CBC not indicated (strong, low) consider based upon
patient’s underlying medication condition and the planned procedure
(e.g. pt has history of anemia or history suggesting recent blood loss
anemia)
ASA says routine Hgb/CBC not indicated, consider based
upon type and invasiveness of procedure, patients with liver disease,
extremes of age, and history of anemia, bleeding, and other hematologic
disorders.
ESA says:
– Routine coagulation test not recommended unless there are specific risk factors in the history (D).
– If coag disorder suspected, patient should be referred to a hematologist (D).
ICSI says coagulation studies are not routinely necessary unless a specific indication is present.
Preoperative
diagnostic spirometry in non-cardiothoracic surgery patients cannot be
recommended to evaluate the risk of postoperative complications (ESA D).
Spirometry
characterizes obstructive lung disease well, but it does not well
predict postoperative complications nor guide demonstrated management
improvements.
ASA says routine urinalysis is not indicated except for specific procedures (e.g., prosthesis implantation, urologic procedures) or when urinary tract symptoms are present
A
recent Canadian guideline (see ref) recommends pre-operative BNP (or
NT-proBNP) and post-operative Troponin on certain (high-risk) patients.
ACC
does not endorse routine screening BNP or Troponin as there is no
evidence as of yet to guide how to respond to the results of such tests
and their potential impact on care for good or ill. However, new
evidence is emerging. A large cohort study nested in the recent VISION
trial looked at preop BNP, postop troponin levels, and the 30-day
outcomes of MINS (myocardial injury after non-cardiac surgery, meaning
symptomatic or non-symptomatic rise of troponin without non-ischemic
alternate cause), vascular death, and all-cause mortality (Duceppe 2019,
see ref). Elevated preop NT-proBNP was associated with elevated risk
of MINS, vascular death, and all-cause mortality. The article suggests
that preop BNP could be used with RCRI to assist in preop risk
stratification. However, no study yet shows that use of this
information pre- or post-op improves outcomes. Pay attention for
further studies and incorporation into guidelines.
Note that if
signs or symptoms of myocardial ischemia or heart failure develop, then
diagnostic testing with these biomarkers and any clinically indicated
evaluation is quite appropriate (and explicitly endorsed by ACC).
Various
authorities have opinions about the value of additional pre-op tests.
For instance, Beta-HCG in reproductive-age women with uncertain
pregnancy status, BUN & Creatinine in patients with suspected or
known renal disease, etc.
Most importantly, if your knowledge of
the patient suggest risk of deranged lytes, renal fxn, pulmonary fxn,
etc., and it bears on surgery, you are justified to check any test.
No routine preop testing is indicated.
A
Cochrane systematic review of 2012 looked specifically at the value of
preop testing before cataract surgery, finding 3 RCT’s of 21,000+ total
patients. It found that patients undergoing cataract surgery did have
adverse medical events associated with surgery, which is not surprising
since patients with cataracts often have numerous other medical
comorbidities. However, routine preop testing did not reduce those
events during or after surgery compared with no testing at all. The
conclusion is that routine preop testing does not improve the safety of
cataract surgery.