2024 Cardiac Algorithm - Step 5

Further Testing - Abnormal Biomarkers

When biomarker(s) are abnormal, ACC recommends once again consideration by care team risks and benefits of further testing. If further testing is elected, consider the following structural and functional evaluation options:

- consider echocardiography
- consider non-invasive stress testing
- consider CCTA


Does further cardiac evaluation reveal low-risk findings or elevated-risk findings?

Low-risk findings 

Non-emergency surgery
No acute coronary syndrome
Elevated risk surgery
Poor/unknown functional capacity
Further testing desired
Abnormal cardiac biomarker(s)
Low-risk findings from further cardiac tests

Proceed to surgery

High-risk findings

Non-emergency surgery
No acute coronary syndrome
Elevated risk surgery
Poor/unknown functional capacity
Further testing desired
Abnormal cardiac biomarker(s)

finally, either...

Hi-risk findings from further cardiac tests
- or -
Deferral of further cardiac testing

For these patients, all options are available for clinician and patient discussion including...
- deferral of surgery
- non-invasive or invasive treatment of cardiac conditions like CAD
- palliative measures
- proceeding to surgery as-is despite suboptimal circumstances

ACC also recommends that for those who head to surgery from this group, post-operative troponin testing can be considered (2b level recommendation). 

Additional cardiac testing deferred

Non-emergency surgery
No acute coronary syndrome
Elevated risk surgery
Poor/unknown functional capacity
Further testing desired
Abnormal cardiac biomarker(s)

finally, either...

Hi-risk findings from further cardiac tests
- or -
Deferral of further cardiac testing

For these patients, all options are available for clinician and patient discussion including...
- deferral of surgery
- non-invasive or invasive treatment of cardiac conditions like CAD
- palliative measures
- proceeding to surgery as-is despite suboptimal circumstances

ACC also recommends that for those who head to surgery from this group, post-operative troponin testing can be considered (2b level recommendation). 

ACC phrases each recommendation in the decision tree with the term "consider" and explicitly grades the stress test and CCTA recommendations as 2b.